[대학원 생명과학과 금요세미나 안내]
연사 : 박재용 교수(고려대학교 의생명융합과학과)
연제 : Emergine roles of TWIK-1 in the brain
일시 : 2016년 4월 15일 (금) 오후 4시
장소 : 하나과학관 A동 109호
초청교수 : 조용철 교수
Abstract
Although TWIK-1 is the first identified member of two-pore domain K+(K2P) channels that play an essential part in the regulation of resting membrane potential and cellular excitability, the physiological roles of TWIK-1 in the brain are recently being studied in depth. A series of our recent studies suggest that TWIK-1 underlie various function such as intrinsic excitability of neurons, astrocytic passive conductance, and astrocytic glutamate release as homodimer or heterodimer with other K2P isotypes. Here, I review newly identified functions of TWIK-1 in the brain based on the recent our studies demonstrating the pivotal functions of TWIK-1.